Willem J. Remme
Pat Illingworth
Karen Keukelaar
Jan A. de Witt
Karen J. Williams
Ralph Hultzer
Dori Kadmon
Regulatory Affairs
Clinical Monitoring
Pharmacovigilance
Clinical Event Management
Medical Review
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Scientific Advisory Board
Biography Dr Williams
Team Expertise
 
 

Scientific Advisory Board

Sticares InterACT combines its full-service CRO capabilities with the clinical expertise and the academic leadership of the Sticares Cardiovascular Research Institute (SCRI). We offer consulting services through thought leadership of SCRI’s academic body, the Scientific Advisory Board.

 

The Scientific Advisory Board consists of internationally renowned academic experts who have made breakthroughs in diagnosis, medical therapy, surgical procedures, and clinical research; all with high-level inroads to pharmaceutical companies, accelerating critical time-to-market for our sponsors.

Our own CEO Professor Willem J. Remme complements the Scientific Advisory Board as an expert in heart failure

 

DR. G.L. BAKRIS DR. M. GHEORGHIADE DR. R.S. ROSENSON DR. H.N. SABBAH DR. J.J.P. KASTELEIN

George L. Bakris, MD, FAHA, FASN, is Professor of Medicine at the University of Chicago School of Medicine in Illinois, and serves as Director of the Hypertension Center in the Diabetes Institute.
Professor Bakris received his medical degree from the Chicago Medical School. He completed his residency in Internal Medicine at the Mayo Graduate School of Medicine, where he also completed a research fellowship in Physiology and Biophysics. He then completed fellowships in Nephrology and Clinical Pharmacology at the University of Chicago.

Professor Bakris specializes in the diagnosis and reduction of high blood pressure, particularly in complicated or refractory cases. He is also skilled in the treatment of kidney disease, with special expertise in diabetes-related kidney disease. Professor Bakris has published over 400 articles and book chapters in the areas of kidney disease, hypertension and progression of nephropathy. He is the Editor or Co-Editor of several books, all dealing with Kidney Diseases, Diabetes and the role of Hypertension. Click here for his publications listed with PubMed.

Mihai Gheorghiade, MD, FACC, FCCP, FACP

 

Dr. Gheorghiade currently serves as Professor of Medicine and Surgery, Director of Experimental Therapeutics at the Center for Cardiovascular Innovation, Division of Cardiology, at Northwestern University’s Feinberg School of Medicine and Northwestern Memorial Hospital.


He was recently appointed Adjunct Professor of Medicine and Co-Director of the new Cardiovascular Center for Drug Development at Duke University. He graduated Magna Cum Laude from the University of Rome Medical School in 1972 and did his residency and fellowship in cardiology at Brown University.  He then moved to Virginia, where he was Chief of Cardiology at the Salem VA Medical Center and Associate Professor of Medicine at the University of Virginia. In 1985, Dr. Gheorghiade became Chief of the Cardiac Care Unit at the Henry Ford Hospital in Detroit and Associate Professor of Clinical Medicine at the University of Michigan. During his tenures in Virginia and Michigan, he received numerous teaching awards from both medical students and residents. In 1992, he joined Northwestern University as Associate Chief of the Division of Cardiology, Chief of the Cardiology Clinical Service, and Director of the Telemetry Unit at Northwestern University Feinberg School of Medicine until 2010

 

Dr. Gheorghiade has served as a visiting professor in the United States and abroad. He has chaired or co-chaired more than 200 national and international meetings and has given more than 500 invited lectures. He has served or is currently serving on the editorial board of several journals including The American Heart Journal, The American Journal of Cardiology, Journal of the American College of Cardiology, and Circulation Heart Failure Journal, and is an associated editor of the Journal of Cardiovascular Medicine. He has also served as guest editor on several occasions for The American Journal of Cardiology, The American Heart Journal, and The American Journal of Medicine. He has chaired many international trials in heart failure including OPTIME-HF, ACTIV-HF, IMPACT, PRESERVD, HORIZON and COMPOSE Trials. He also co-chaired the global EVEREST Trial and the ECLIPSE Trial, and was a member of the Steering Committee of RADIANCE, FIRST, CARS, RITZ 4, and EPHESUS Trial. In addition, Dr. Gheorghiade was an active member of the Steering Committee in the OPTIMIZE-HF and IMPACT-HF registries. He currently serves as Chair of the international ASTRONAUT, RENO-DEFEND, and IMPROVE-HF Bridge.

 

 Dr. Gheorghiade has authored more than 500 peer-reviewed publications and more than 300 abstract presentations at national and international meetings. He is the co-editor for two comprehensive textbooks on acute heart failure syndromes and has written several chapters in many textbooks including Kelley’s Textbook of Internal Medicine, and Heart Failure: A Companion to Braunwald’s Heart Disease, and most recently authored the chapter on Acute Heart Failure Syndromes in the ninth edition of Braunwald’s Heart Disease.

In 2004, Dr. Gheorghiade founded the Acute Heart Failure Syndromes International Group, comprised of physicians, scientists, clinicians, and regulatory and governmental agencies from North America and Europe to advance the knowledge and care of patients with acute heart failure syndromes through clinical research. This group has met annually, producing several consensus documents published in Circulation, Journal of the American College of Cardiology, and European Heart Journal.

 

In 2011, Dr. Gheorghiade assembled The Academic Research Team in Heart Failure(ART –HF)  a group of expert clinicians and researchers with complimentary expertise to guide the development of heart failure therapeutics spanning the spectrum ranging from pre-clinical, phase I-III, and post marketing studies; to regulatory and guideline process

and remains actively involved in animal and human research for the development of novel compounds for acute heart failure syndromes. He dedicates significant time and energy to the mentorship of medical students, residents and junior faculty as attested by their primary authorship of more than 100 peer-reviewed publications in recent years. Improving outcomes of hospitalized patients with heart failure through research and education remains his top priorities.

 

Professor of Medicine and Cardiology Robert S. Rosenson, MD, PhD, FACC, FAHA, currently resides in Professor Fuster’s Mount Sinai Heart at The Mount Sinai Medical Center in New York City.

Before joining Mount Sinai Heart, he was Professor of Medicine and Director of Lipoprotein Disorders and Clinical Atherosclerosis Research & Cardiovascular Diseases at the University of Michigan in Ann Arbor.

His clinical research has investigated the effects of lipid-lowering therapies‚ hypoglycemic therapies and antihypertensive agents on inflammation and thrombogenesis as well as the effects of hyplolipidemic and antihypertensive agents on blood viscosity and fibrinogen. Previously‚ he was Professor of Cardiology at Northwestern University Medical School‚ where he also served as Director of the Preventative Cardiology Center and Director of the Lipoprotein and Hemorheology Research Facility. He has published over 70 peer-reviewed scientific papers and nearly 70 book chapters in the field. He also serves as an editor of a number of journals including Atherosclerosis. Click here for his publications listed with PubMed.

Professor of Cardiology Hani N. Sabbah, PhD, FACC, FAHA, is the current director of the Cardiovascular Research Laboratories at Henry Ford Health System of the Henry Ford Hospital in Detroit.

The Cardiovascular Research Laboratories at Henry Ford Health System function as a multidisciplinary center fully focused on understanding the pathophysiology of heart failure and on the development and testing of novel therapeutic modalities for the treatment of this disease syndrome. Dr. Hani N. Sabbah is tenured Professor of Medicine at Wayne State University in Detroit, Michigan.


He is the author of over 20 book chapters, over 300 peer reviewed publications and over 500 abstract presented at national and international scientific conferences. Dr. Sabbah is member of the editorial board of several peer-reviewed scientific journals and is the Co Editor-in-Chief of the journal Heart Failure Reviews. Click here for his publications listed with PubMed.

John J.P. Kastelein is Professor of Medicine and chairman of the Department of Vascular Medicine at the Academic Medical Center (AMC) of the University of Amsterdam, where he holds the Strategic Chair of Genetics of Cardiovascular Disease.

He received his medical degree in Amsterdam in 1980 where he subsequently received specialty training in internal medicine. Then, between 1986 and 1988, he was trained in medical genetics, lipidology and molecular biology at the University of British Columbia, Vancouver under the guidance of Prof. Dr. M.R. Hayden.

 

Upon his return to the Netherlands, he was awarded a doctorate (Cum Laude) and in 1989 he founded the Lipid Research Clinic at the Academic Medical Centre in Amsterdam, which is currently serving as a tertiary referral centre for over 5000 patients each year and has become part of the department of Vascular Medicine.

 

Dr. Kastelein is president of the Dutch Atherosclerosis Society (DAS) and chairs the National Scientific Committee on Familial Hypercholesterolemia (EHC). He also is a member of the Royal Dutch Society for Medicine & Physics, the Council for Basic Science of the American Heart Association and the European Atherosclerosis Society. He also is a board member of the International Task Force for CHD Prevention and was recently appointed to the Executive Board of the International Atherosclerosis Society (IAS).

Professor Kastelein’s current research interests can be found in the etiology, diagnosis, prevention and treatment of hypertriglyceridaemia, hypercholesterolaemia and low HDL cholesterol, all conditions associated with atherosclerosis and cardiovascular disease. He has published over 540 research papers in peer reviewed journals, including Nature Genetics, Lancet, New England Journal of Medicine, JAMA and Circulation and has a Hirsch index of 55.

 

Besides the scientific programs aimed at the etiology of atherogenesis, Dr. Kastelein also serves on a number of executive and steering committees of large intervention studies, including the IDEAL, TNT, CAPTIVATE, ENHANCE, ILLUMINATE, JUPITER, RADIANCE and numerous others of which TNT (2005), RADIANCE 1 (2007), ENHANCE (2008) and JUPITER (2008) are published in the New England Journal of Medicine, IDEAL (2006) in JAMA and RADIANCE 2 (2007) in Lancet

 
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